Research Use Only. Peptides Lab UK supplies research-grade materials for in-vitro laboratory research only. Nothing on this page is medical advice or an instruction for human or animal use, and no product sold on this website is a medicine.
What is Glutathione?
Glutathione (γ-glutamyl-cysteinyl-glycine) is an endogenous tripeptide and the most abundant low-molecular-weight thiol in mammalian cells, central to cellular redox homeostasis and detoxification reactions.
Published research
Reviews describe glutathione’s biosynthesis from glutamate, cysteine and glycine, its role in buffering reactive oxygen species and its compartmentalised function in mitochondria. A dermatology review examined the evidence behind cosmetic claims and found it limited and inconsistent.[1,2,3,4]
Limitations of the evidence
Much of the available literature is preclinical (cell and animal models) or comes from small numbers of research groups. Findings in defined experimental systems cannot be extrapolated to other settings, and this page does not provide dosing, administration or human-use information.
Laboratory handling and storage
Lyophilised peptides are generally stored sealed, protected from light and moisture, at low temperature as specified on the certificate of analysis. Once reconstituted for in-vitro work, solutions are typically kept refrigerated and used within a validated stability window. Researchers should follow their institution’s procedures and the batch documentation (HPLC purity and mass-spectrometry identity) supplied with each lot.
UK regulatory status
In the UK, medicines are regulated by the Medicines and Healthcare products Regulatory Agency (MHRA). Research-grade compounds sold by Peptides Lab UK are supplied strictly for laboratory research; they are not medicinal products, are not manufactured to medicinal GMP standards and must not be used in humans or animals.
Related research pages
References
- Gasmi A et al. An Update on Glutathione's Biosynthesis, Metabolism, Functions, and Medicinal Purposes. Curr Med Chem. 2024; 31(29):4579-4601. doi:10.2174/0109298673251025230919105818 PMID: 37921175.
- Chen TH et al. Mitochondrial Glutathione in Cellular Redox Homeostasis and Disease Manifestation. Int J Mol Sci. 2024; 25(2). doi:10.3390/ijms25021314 PMID: 38279310.
- Sies H et al. Oxidative Stress. Annu Rev Biochem. 2017; 86:715-748. doi:10.1146/annurev-biochem-061516-045037 PMID: 28441057.
- Sonthalia S et al. Glutathione as a skin whitening agent: Facts, myths, evidence and controversies. Indian J Dermatol Venereol Leprol. 2016; 82(3):262-72. doi:10.4103/0378-6323.179088 PMID: 27088927.
Disclaimer: All products sold by Peptides Lab UK are for laboratory research use only. Not for human or veterinary use, not for consumption, and not intended to diagnose, treat, cure or prevent any disease. This page is an educational literature summary and is not medical advice.
